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Two siblings with an unusual nasal malformation: Further instances of craniorhiny?
Author(s) -
Lees Melissa M.,
Kangesu Loshan,
Hall Per,
Hennekam Raoul C.M.
Publication year - 2007
Publication title -
american journal of medical genetics part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.064
H-Index - 112
eISSN - 1552-4833
pISSN - 1552-4825
DOI - 10.1002/ajmg.a.32026
Subject(s) - hypertelorism , philtrum , anatomy , medicine , sibling , nose , skull , tongue , pathology , upper lip , psychology , developmental psychology
We report a brother and sister born to consanguineous parents. The siblings have hypertelorism, bifid nose, upturned nares, histologically proven intranasal dermoid, and soft‐tissue swellings of the philtrum. One sibling also has a midline cleft lip and the other has narrowing of the posterior choanae. We suggest that they have craniorhiny, despite the absence of an abnormal skull shape. The differential diagnosis is discussed. © 2007 Wiley‐Liss, Inc.