Premium
Visualization of human prenatal development by magnetic resonance imaging (MRI)
Author(s) -
Shiota Kohei,
Yamada Shigehito,
NakatsuKomatsu Tomoko,
Uwabe Chigako,
Kose Katsumi,
Matsuda Yoshimasa,
Haishi Tomoyuki,
Mizuta Shinobu,
Matsuda Tetsuya
Publication year - 2007
Publication title -
american journal of medical genetics part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.064
H-Index - 112
eISSN - 1552-4833
pISSN - 1552-4825
DOI - 10.1002/ajmg.a.31994
Subject(s) - magnetic resonance imaging , visualization , process (computing) , microscope , high resolution , computer science , magnetic resonance microscopy , biomedical engineering , computer vision , nuclear magnetic resonance , artificial intelligence , medicine , radiology , pathology , physics , remote sensing , spin echo , geology , operating system
It is essential to visualize the structures of embryos and their internal organs three‐dimensionally to analyze morphogenesis; this used to rely solely on serial histological sectioning and solid reconstruction, which were tedious and time‐consuming. We have applied imaging with a magnetic resonance (MR) microscope equipped with a 2.35 T superconducting magnet to visualize human embryos; we were successful in acquiring high‐resolution sectional images and in identifying the detailed structures of major organs. The imaging process was facilitated by using a super‐parallel MR microscope. A dataset of MR images of more than 1,000 human embryos, now collected, will be important for future biomedical research and for education. © 2007 Wiley‐Liss, Inc.