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Metabolic and molecular basis of peroxisomal disorders: A review
Author(s) -
Wanders Ronald J.A.
Publication year - 2004
Publication title -
american journal of medical genetics part a
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 1.064
H-Index - 112
eISSN - 1552-4833
pISSN - 1552-4825
DOI - 10.1002/ajmg.a.20661
Subject(s) - peroxisomal disorder , zellweger syndrome , peroxisome , biogenesis , biology , medicine , bioinformatics , genetics , gene
Abstract The group of peroxisomal disorders now includes 17 different disorders with Zellweger syndrome as prototype. Thanks to the explosion of new information about the functions and biogenesis of peroxisomes, the metabolic and molecular basis of most of the peroxisomal disorders has been resolved. A review of peroxisomal disorders is provided in this paper. © 2004 Wiley‐Liss, Inc.