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Liver disease following occupational exposure to 1,1,1‐trichloroethane: A case report
Author(s) -
Cohen Chaim,
Frank Arthur L.
Publication year - 1994
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/ajim.4700260209
Subject(s) - medicine , cirrhosis , alcoholic liver disease , liver disease , chronic liver disease , etiology , occupational exposure , liver function tests , occupational disease , liver function , liver dysfunction , disease , occupational medicine , toxicity , gastroenterology , physiology , pathology , environmental health
A patient with a progressive liver disease whose job involved substantial exposure to 1,1,1‐trichloroethane (TCE) was seen. A comprehensive work‐up ruled out nonoccupational etiologies for his liver condition. Neither the patient's history nor his liver histology suggested alcoholic cirrhosis. Removal of the patient from exposure to TCE led to significant improvement of his impaired liver function over a 3‐month period. We conclude that this was a case of occupational liver disease induced by chronic exposure to TCE. This report joins other reports concerning hepatotoxicity of TCE which is considered the least toxic among the halogenated hydrocarbon solvents.