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Relationship of lung geometry to the development of pleural abnormalities in insulation workers exposed to asbestos
Author(s) -
Delfino Ralph,
Ernst Pierre,
Bourbeau Jean
Publication year - 1989
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/ajim.4700150406
Subject(s) - medicine , asbestos , lung , abnormality , chest radiograph , radiography , logistic regression , asbestosis , respiratory disease , airway , lung disease , geometry , pathology , radiology , surgery , mathematics , materials science , psychiatry , metallurgy
Abstract The relationship of respiratory airway and airspace geometry to radiographic evidence of pleural abnormality consistent with asbestos exposure was studied in 178 construction insulators. Lung geometry was assessed from tracings of radiographic shadows, and the measures taken were tracheal length and diameter, subcarinal angle, right and left lung lengths, and upper, middle, and lower lung widths. Important modifying variables—age, height, weight, exposure estimates, and smoking history—were included in a logistic regression model to test the significance of the lung geometry measurements as predictors of the presence or absence of pleural abnormality. No such relationships were found. Neither were there any differences in prevalence or severity of pleural disease between the right and left sides which might have been found if airway geometry were a significant determinant of asbestos pleural disease. These results do not support the hypothesis that lung geometry is a host risk factor for the development of asbestos‐related pleural disease.