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Histologic Types of Lung Cancers Among Male Japanese Copper Smelter Workers
Author(s) -
Tokudome Shinkan,
Haratake Joji,
Horie Akio,
Era Shoichi,
Fujii Hideharu,
Kawachi Jitsuyo,
Miyamoto Yuichi,
Suko Shuji,
Tokunaga Masayoshi,
Tsuji Koichi,
Ikeda Masato
Publication year - 1988
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/ajim.4700140204
Subject(s) - medicine , lung cancer , basal cell , pathology , bronchogenic carcinoma , lung , carcinoma , small cell carcinoma , large cell , cancer , oncology , adenocarcinoma
This study was done to investigate which histologic type of lung cancer is prevalent among male Japanese copper smelter workers. A panel of eight pathologists was asked to diagnose uniformly prepared materials for 19 occupational series, 87 nonoccupational bronchogenic carcinomas, and 14 benign lesions. The consensus diagnosis was used as reference. The reference diagnoses and the originals without materials employed for verification were designated as finals. Squamous cell carcinoma was the most frequent cell type in the occupational group, which comprised 21 (75.0%) of 28 histologically proven cases. There were three (10.7%) small cell carcinomas, one (3.6%) large cell carcinoma, and three (10.7%) adenocarcinomas. The proportion of Kreyberg group I in the occupational cases was significantly larger than that of lung cancers in the population‐based cancer registries in Japan. These findings are compatible with Kreyberg's hypothesis. Above all, squamous and small cell carcinomas were prominent and appeared to be environmentally related bronchogenic carcinomas.