Premium
Cancer incidence and mortality among workers exposed to acrylonitrile
Author(s) -
Chen Jean L.,
Walrath Judy,
O'Berg Maureen T.,
Burke Cheryl A.,
Pell Sidney
Publication year - 1987
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/ajim.4700110205
Subject(s) - medicine , lung cancer , incidence (geometry) , cancer , demography , prostate cancer , cohort , mortality rate , cancer incidence , surgery , toxicology , physics , sociology , optics , biology
A cohort of 1,083 male employees who had potential for exposure to acrylonitrile between 1944 and 1970 at a Du Pont textile fibers plant were followed through 1981 for mortality and through 1983 for cancer incidence. In total, the 21 cancer deaths were fewer than expected based on either Du Pont or U.S. rates. No significant excesses were seen by primary site. In all, 37 cancer cases occurred as compared with 36.5 expected based on company rates. Five lung cancer cases were observed and 6.9 expected. There were 5 prostate cancer cases as compared with 1.9 expected. Of these, 4 occurred among wage employees during the 1975‐1983 period, compared to 0.9 expected. This excess was statistically significant.