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Occupational exposure to textile dust and lung cancer risk: Results from the ICARE Study
Author(s) -
Ben Khedher Soumaya,
Neri Monica,
Guida Florence,
Matrat Mireille,
Cenée Sylvie,
Sanchez Marie,
Radoi Loredana,
Menvielle Gwenn,
Marrer Emilie,
Luce Danièle,
Stücker Isabelle
Publication year - 2018
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/ajim.22799
Subject(s) - medicine , lung cancer , odds ratio , asbestos , confidence interval , confounding , environmental health , logistic regression , occupational exposure , case control study , population , materials science , metallurgy
Background To investigate the association of lung cancer with occupational exposure to textile dust and specifically to cotton dust in the population‐based case‐control study ICARE. Methods Lifelong occupational history of 2926 cases and 3555 controls was collected using standardized questionnaires, with specific questions for textile dust exposure. Odds ratios (ORs) and 95% confidence intervals (CI) were estimated using unconditional logistic regression models controlling for confounding factors including smoking and asbestos exposure. Results An inverse association between textile dust exposure and lung cancer was found among workers exposed ≥5% of their work time (OR = 0.80, 95%CI = 0.58‐1.09), more pronounced for distant exposures (40+ years; up to a 56% reduced risk, statistically significant). The OR of lung cancer was significantly decreased among workers exposed to cotton fibers (OR = 0.70, 95%CI = 0.48‐0.97). Conclusions Our results provide some evidence of a decreased risk of lung cancer associated with exposure to textile dust, particularly cotton.