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Sinonasal cancer in the Italian national surveillance system: Epidemiology, occupation, and public health implications
Author(s) -
Binazzi Alessandra,
Corfiati Marisa,
Di Marzio Davide,
Cacciatore Anna M.,
Zajacovà Jana,
Mensi Carolina,
Galli Paolo,
Miligi Lucia,
Calisti Roberto,
Romeo Elisa,
Franchi Alessandro,
Marinaccio Alessandro
Publication year - 2018
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/ajim.22789
Subject(s) - medicine , epidemiology , environmental health , etiology , incidence (geometry) , occupational exposure , occupational disease , occupational medicine , public health , pathology , physics , optics
Background Sinonasal cancer (SNC) is a rare tumor with predominant occupational etiology associated with exposures to specific carcinogens. The aim of this study is to describe SNC cases recorded in Italy in the period 2000‐2016. Methods Clinical information, occupational history, and lifestyle habits of SNC cases collected in the Italian Sinonasal Cancer Register were examined. Age‐standardized rates were estimated. Results Overall, 1529 cases were recorded. The age‐standardized incidence rates per 100 000 person‐years were 0.65 in men and 0.26 in women. Occupational exposures were predominant among the attributed exposure settings, primarily to wood and leather dusts. Other putative causal agents included chrome, solvents, tannins, formaldehyde, textile dusts, and pesticides. Many cases had unknown exposure. Conclusions Epidemiological surveillance of SNC cases and their occupational history is fundamental for monitoring the occurrence of the disease in exposed workers in industrial sectors generally not considered at risk of SNC as well as in non‐occupational settings.