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Dupuytren's contracture and handwork: A case‐control study
Author(s) -
Haines Alfred,
Levis Carolyn,
Goldsmith Charles H.,
Kaur Manraj,
Duku Eric,
Wells Richard,
Walter Stephen D.,
Rook Cheryl,
Stock Susan,
Liss Gary,
Murphy Jessica,
Thoma Achilleas
Publication year - 2017
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/ajim.22736
Subject(s) - medicine , logistic regression , heredity , case control study , family history , risk factor , dupuytren's contracture , intensity (physics) , surgery , contracture , genetics , physics , quantum mechanics , biology
Objective The objective of this study was to examine the association between Dupuytren's contracture (DC), repetitive handwork (RHW), heavy handwork (HHW), and/or vibration exposure. Methods Frequency and intensity of the three types of handwork were collected and compared between DC patients and controls. Hours of work were weighted by average “frequency,” for RHW, and average “intensity,” for HHW and use of vibrating tool. Logistic regression was used to evaluate risk of developing DC associated with the above‐mentioned factors. Results Data from 129 cases (74 clinical, 106 controls) was analyzed. Family history, male gender and age (decades) were associated with increased risk of DC. Results indicate that the risk becomes substantial after about 30 years of steady RHW. Independent effects of intensity‐weighted HHW and vibrating exposure were not established. Conclusions Frequency‐weighted RHW increases DC risk. Additionally, a strong association between DC, male gender and heredity was found.