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Ten‐year cancer incidence in rescue/recovery workers and civilians exposed to the September 11, 2001 terrorist attacks on the World Trade Center
Author(s) -
Li Jiehui,
Brackbill Robert M.,
Liao Tim S.,
Qiao Baozhen,
Cone James E.,
Farfel Mark R.,
Hadler James L.,
Kahn Amy R.,
Konty Kevin J.,
Stayner Leslie T.,
Stellman Steven D.
Publication year - 2016
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/ajim.22638
Subject(s) - medicine , world trade center , terrorism , incidence (geometry) , environmental health , cancer , cancer incidence , occupational safety and health , center (category theory) , occupational exposure , medical emergency , emergency medicine , pathology , physics , archaeology , optics , history , chemistry , crystallography
Background Cancer incidence in exposed rescue/recovery workers (RRWs) and civilians (non‐RRWs) was previously reported through 2008. Methods We studied occurrence of first primary cancer among World Trade Center Health Registry enrollees through 2011 using adjusted standardized incidence ratios (SIRs), and the WTC‐exposure‐cancer association, using Cox proportional hazards models. Results All‐cancer SIR was 1.11 (95% confidence interval (CI) 1.03–1.20) in RRWs, and 1.08 (95% CI 1.02–1.15) in non‐RRWs. Prostate cancer and skin melanoma were significantly elevated in both populations. Thyroid cancer was significantly elevated only in RRWs while breast cancer and non‐Hodgkin's lymphoma were significantly elevated only in non‐RRWs. There was a significant exposure dose‐response for bladder cancer among RRWs, and for skin melanoma among non‐RRWs. Conclusions We observed excesses of total and specific cancers in both populations, although the strength of the evidence for causal relationships to WTC exposures is somewhat limited. Continued monitoring of this population is indicated. Am. J. Ind. Med. 59:709–721, 2016. © 2016 Wiley Periodicals, Inc.