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Post‐9/11 cancer incidence in World Trade Center‐exposed New York City firefighters as compared to a pooled cohort of firefighters from San Francisco, Chicago and Philadelphia (9/11/2001‐2009)
Author(s) -
Moir William,
ZeigOwens Rachel,
Daniels Robert D.,
Hall Charles B.,
Webber Mayris P.,
Jaber Nadia,
Yiin James H.,
Schwartz Theresa,
Liu Xiaoxue,
Vossbrinck Madeline,
Kelly Kerry,
Prezant David J.
Publication year - 2016
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/ajim.22635
Subject(s) - medicine , world trade center , demography , poisson regression , cohort , relative risk , cancer , population , incidence (geometry) , environmental health , gerontology , confidence interval , physics , archaeology , sociology , terrorism , optics , history
Background We previously reported a modest excess of cancer in World Trade Center (WTC)‐exposed firefighters versus the general population. This study aimed to separate the potential carcinogenic effects of firefighting and WTC exposure by comparing to a cohort of non‐WTC‐exposed firefighters. Methods Relative rates (RRs) for all cancers combined and individual cancer subtypes from 9/11/2001 to 12/31/2009 were modeled using Poisson regression comparing 11,457 WTC‐exposed firefighters to 8,220 urban non‐WTC‐exposed firefighters. Results Compared with non‐WTC‐exposed firefighters, there was no difference in the RR of all cancers combined for WTC‐exposed firefighters (RR = 0.96, 95%CI: 0.83–1.12). Thyroid cancer was significantly elevated (RR = 3.82, 95%CI: 1.07–20.81) from 2001 to 2009; this was attenuated (RR = 3.43, 95%CI: 0.94–18.94) and non‐significant when controlling for possible surveillance bias. Prostate cancer was elevated during the latter half (2005–2009; RR = 1.38, 95%CI: 1.01–1.88). Conclusions Further follow‐up is needed to assess the relationship between WTC exposure and cancers with longer latency periods. Am. J. Ind. Med. 59:722–730, 2016. © 2016 Wiley Periodicals, Inc.