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Occupational exposures to engine exhausts and other PAHs and breast cancer risk: A population‐based case‐control study
Author(s) -
Rai Rajni,
Glass Deborah C.,
Heyworth Jane S.,
Saunders Christobel,
Fritschi Lin
Publication year - 2016
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/ajim.22592
Subject(s) - medicine , breast cancer , odds ratio , environmental health , confidence interval , occupational medicine , case control study , population , diesel engine , logistic regression , diesel exhaust , occupational exposure , cancer , demography , automotive engineering , engineering , sociology
Background Some previous studies have suggested that exposure to engine exhausts may increase risk of breast cancer. Methods In a population‐based case‐control study of breast cancer in Western Australia we assessed occupational exposure to engine exhausts using questionnaires and telephone interviews. Odds Ratios (OR) and 95% Confidence Intervals (CI) were calculated using logistic regression. Results We found no association between risk of breast cancer and occupational exposure to diesel exhaust (OR 1.07, 95%CI: 0.81–1.41), gasoline exhaust (OR 0.98, 95%CI: 0.74–1.28), or other exhausts (OR 1.08, 95%CI: 0.29–4.08). There were also no significant dose‐ or duration‐response relationships. Conclusions This study did not find evidence supporting the association between occupational exposures to engine exhausts and breast cancer risk. Am. J. Ind. Med. 59:437–444, 2016. © 2016 Wiley Periodicals, Inc.