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Triticale allergy in a farmer
Author(s) -
Merget Rolf,
Sander Ingrid,
van Kampen Vera,
Raulf Monika,
Brüning Thomas
Publication year - 2016
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/ajim.22567
Subject(s) - triticale , medicine , hay fever , allergy , immunoglobulin e , plant lipid transfer proteins , pollen , sensitization , asthma , immunology , exhaled nitric oxide , agronomy , spirometry , antibody , botany , biology , biochemistry , gene
We present the case of a 29‐year‐old farmer with hay fever and atopic dermatitis since adolescence who had developed work‐related asthma about 5 years earlier. He was sensitized to grass pollen, wheat and rye flour, dust from the floors of the animal facilities (cows and pigs) and grain barn, and a battery of animal feed from his farm. Work‐relatedness of his asthma was demonstrated by serial measurements of spirometry and fractional exhaled nitric oxide at work and during a holiday. Immunoblot analyses revealed dominant IgE‐binding to grass pollen and triticale (a hybrid of rye and wheat). IgE inhibition experiments demonstrated that sensitization to triticale was not due to cross‐reactivity to grass pollen. Testing of specific IgE‐antibodies to recombinant wheat allergens showed sensitizations to profilin, peroxidase, and nonspecific lipid transfer proteins type I subfamily 9.1 and 9.7. We conclude that triticale allergy may occur as a distinct allergy in farmers. Am. J. Ind. Med. 59:501–505, 2016. © 2016 Wiley Periodicals, Inc.