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Asbestos textile production linked to malignant peritoneal and pleural mesothelioma in women: Analysis of 28 cases in Southeast China
Author(s) -
Gao Zhibin,
Hiroshima Kenzo,
Wu Xiaodong,
Zhang Jixian,
Shao Dichu,
Shao Huajiang,
Yang Hanqing,
Yusa Toshikazu,
Kiyokawa Takako,
Kobayashi Makio,
Shinohara Yasushi,
Røe Oluf D.,
Zhang Xing,
Morinaga Kenji
Publication year - 2015
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/ajim.22494
Subject(s) - mesothelioma , asbestos , medicine , chrysotile , peritoneal mesothelioma , tremolite , china , pathology , materials science , political science , law , metallurgy
Background Chrysotile had been used in asbestos textile workshops in Southeast China but a clear relation to mesothelioma is lacking. Methods All patients diagnosed with mesothelioma from 2003 to 2010 at Yuyao People's Hospital were re‐evaluated by multiple expert pathologists with immunohistochemistry and asbestos exposure data were collected. Results Of 43 patients with a mesothelioma diagnosis, 19 peritoneal and nine pleural cases were finally diagnosed as mesothelioma. All were females, and the mean age of the patients with peritoneal or pleural mesothelioma was 52.4 and 58.2 years, respectively. All these cases had a history of domestic or occupational exposure to chrysotile. Two‐thirds of the patients were from two adjoining towns with multiple small asbestos textile workshops. Contamination of tremolite was estimated to be less than 0.3%. Conclusions This is a report of mesothelioma in women exposed to chrysotile asbestos at home and at work, with an over‐representation of peritoneal mesothelioma. Am. J. Ind. Med. 58:1040–1049, 2015. © 2015 Wiley Periodicals, Inc.