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High eosinophil levels and poor evolution in occupational asthma due to cyanoacrylate exposure
Author(s) -
Andujar Ruben,
Cruz MaríaJesús,
Villar Ana,
Morell Ferran,
Muñoz Xavier
Publication year - 2011
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/ajim.20953
Subject(s) - cyanoacrylate , medicine , occupational asthma , cyanoacrylates , inhalation , asthma , eosinophil , occupational exposure , allergy , pulmonary function testing , dermatology , surgery , immunology , anesthesia , environmental health , chemistry , adhesive , organic chemistry , layer (electronics)
We present the case of a 41‐year‐old woman who developed occupational asthma (OA) due to cyanoacrylate while working in a company that manufactured and marketed plastic products. Specific inhalation challenge confirmed the diagnosis of OA to cyanoacrylate. The patient expressed marked eosinophilic inflammation and marked deterioration of pulmonary function while in persistent contact with the causal agent. The possible etiologic mechanisms implicated in the origin of this type of OA are discussed. Patients diagnosed with this condition are advised to avoid exposure to cyanoacrylates. Am. J. Ind. Med. 54:714–718, 2011. © 2011 Wiley‐Liss, Inc.