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Occupation and breast cancer risk in Polish women: A population‐based case‐control study
Author(s) -
Peplonska Beata,
Stewart Patricia,
SzeszeniaDabrowska Neonila,
Rusiecki Jennifer,
GarciaClosas Montserrat,
Lissowska Jolanta,
BardinMikolajczak Alicja,
Zatonski Witold,
Gromiec Jan,
Brzeznicki Slawomir,
Brinton Louise A.,
Blair Aaron
Publication year - 2007
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/ajim.20420
Subject(s) - medicine , breast cancer , odds ratio , confounding , case control study , demography , occupational medicine , logistic regression , population , cancer , etiology , epidemiology , environmental health , gynecology , sociology
Background The etiology of breast cancer is not well understood and the role of occupational exposures in breast carcinogenesis is still uncertain. Methods The population‐based case‐control study included 2,386 incident breast cancer cases diagnosed in 2000–2003, and 2,502 controls. Lifetime occupational histories and information on other potential breast cancer risk factors were obtained through personal interviews. Conditional logistic regression analyses calculated odds ratios (ORs) associated with various occupations and industries after control for potential confounders. Results We found statistically significant excesses of breast cancer among engineers (OR=2.0; 95% CI: 1.0–3.8), economists (2.1; 1.1–3.8), sales occupations‐retail (1.2; 1.0–1.5), and other sales occupations (1.2; 1.0–1.5). Industries showing significantly elevated risks included special trade contractors (2.2; 1.2–4.3), electronic and electric equipment manufacturers (1.7; 1.1–2.7); and public administration/general government n.e.c. (2.7; 1.3–5.7). Each of these findings was supported by a statistically significant positive trend for duration of employment (P<0.05). A decreased breast cancer risk was observed in janitors and cleaners (0.7; 0.5–0.8). Conclusions In this study, we found few associations for breast cancer and occupations or industries. The suggestive findings for the electronic and electric equipment manufacturing industry and for the occupations with potential exposure to magnetic fields deserve further evaluation. Am. J. Ind. Med. 50:97–111, 2007. © 2006 Wiley‐Liss, Inc.