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Occupational exposure to diesel and gasoline engine exhausts and risk of lung cancer among Finnish workers
Author(s) -
Guo Johannes,
Kauppinen Timo,
Kyyrönen Pentti,
Lindbohm MarjaLiisa,
Heikkilä Pirjo,
Pukkala Eero
Publication year - 2004
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/ajim.20013
Subject(s) - medicine , job exposure matrix , lung cancer , diesel exhaust , environmental health , poisson regression , diesel engine , asbestos , occupational medicine , occupational exposure , toxicology , demography , population , automotive engineering , materials science , sociology , engineering , metallurgy , biology
Background Studies on engine exhausts and lung cancer have given inconsistent results. Methods Economically active Finns were followed‐up for lung cancer during 1971–95 (33,664 cases). Their Census occupations in 1970 were converted to exposures to diesel and gasoline engine exhausts with a job–exposure matrix. The relative risks (RRs) for cumulative exposure (CE) were defined by Poisson regression, adjusted for smoking, asbestos, and quartz dust exposure, and socioeconomic status. Results RR for engine exhausts among men did not increase with increasing CE. In women, RR for gasoline engine exhaust was 1.58 (95% CI 1.10–2.26) in the CE‐category of 1–99 mg/m 3 ‐y and 1.66 (1.11–2.50) among those with ≥100 mg/m 3 ‐y (lag 20 years). With a lag of 10 years RR for the middle/highest diesel exhaust category in women was 1.42 (0.94–2.13). Conclusions Occupational exposure to engine exhausts was not consistently associated with lung cancer in this study, possibly due to low exposure levels. Am. J. Ind. Med. 45:483–490, 2004. © 2004 Wiley‐Liss, Inc.