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Problems and Pitfalls in Conducting Epidemiological Research in the Area of Reproductive Toxicology
Author(s) -
Levin Stephen M.
Publication year - 1983
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/ajim.1983.4.1-2.349
Subject(s) - medicine , environmental health , tragedy (event) , limiting , reproductive health , epidemiology , strengths and weaknesses , public health , reproductive toxicity , toxicology , population , psychiatry , pathology , psychology , social psychology , biology , mechanical engineering , toxicity , engineering
Defective reproductive outcome continues to represent a considerable public health burden, as well as a source of intense personal tragedy and enormous expense in our society.Evidence suggests that the rate or reproductive failure may be modifiable, in part by limiting human exposure to environmental agents toxic to the reproductive process. Methodological problems posing difficulties to researchers investigating the association between exposure to such agents and adverse reproductive outcome are discussed, includinginadequacies in existing data bases available for analysis; bias in reporting by or in the collection of information From affected families: and weaknesses in the selection of study populat ions. “control” groups, and outcomes chosen for observation. Suggestions For possible resolution of some of these difficulties are discussed.