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Pulmonary effects of welding fumes: Review of worker and experimental animal studies
Author(s) -
Antonini James M.,
Lewis Anthony B.,
Roberts Jenny R.,
Whaley David A.
Publication year - 2003
Publication title -
american journal of industrial medicine
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.7
H-Index - 104
eISSN - 1097-0274
pISSN - 0271-3586
DOI - 10.1002/ajim.10194
Subject(s) - medicine , welding , occupational exposure , inhalation , environmental health , occupational medicine , toxicology , intensive care medicine , anesthesia , metallurgy , materials science , biology
Background Approximately one million workers worldwide perform welding as part of their work duties. Electric arc welding processes produce metal fumes and gases which may be harmful to exposed workers. Methods This review summarizes human and animals studies which have examined the effect of welding fume exposure on respiratory health. An extensive search of the scientific and occupational health literature was performed, acquiring published articles which examined the effects of welding on all aspects of worker and laboratory animal health. The databases accessed included PubMed, Ovid, NIOSHTIC, and TOXNET. Results Pulmonary effects observed in full‐time welders have included metal fume fever, airway irritation, lung function changes, susceptibility to pulmonary infection, and a possible increase in the incidence of lung cancer. Although limited in most cases, animal studies have tended to support the findings from epidemiologic studies. Conclusions Despite the numerous studies on welding fumes, incomplete information still exists regarding the causality and possible underlying mechanisms associated with welding fume inhalation and pulmonary disease. The use of animal models and the ability to control the welding fume exposure in toxicology studies could be utilized in an attempt to develop a better understanding of how welding fumes affect pulmonary health. Am. J. Ind. Med. 43:350–360, 2003. Published 2003 Wiley‐Liss, Inc.