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Analysis of apoB, HLADQ alpha, and D1S80 polymorphisms in the Italian population using the polymerase chain reaction
Author(s) -
Novelli Giuseppe,
Spinella Aldo,
Gennarelli Massimo,
Mingarelli Rita,
Dallapiccola Bruno
Publication year - 1992
Publication title -
american journal of human biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.559
H-Index - 81
eISSN - 1520-6300
pISSN - 1042-0533
DOI - 10.1002/ajhb.1310040314
Subject(s) - polymerase chain reaction , apolipoprotein b , population , genetics , biology , microbiology and biotechnology , medicine , gene , biochemistry , environmental health , cholesterol
Allele and genotype frequencies of three highly polymorphic loci (apoB, HLADQ alpha, D1S80) have been determined in an Italian sample using the polymerase chain reaction (PCR) amplification and non‐radioactive detection. The allele frequencies ranged from 0.1% to 39%, with an average heterozygosity of 0.74 and a power of discrimination ranging from 0.90 to 0.98. These results are of value for forensic and genetic studies. © 1992 Wiley‐Liss, Inc.