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New STR at the D5S373 locus and its relevance in human population studies
Author(s) -
Luis J.R.,
Dios S.,
Carril J.C.,
Herrera R.,
Caeiro B.
Publication year - 2002
Publication title -
american journal of human biology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 0.559
H-Index - 81
eISSN - 1520-6300
pISSN - 1042-0533
DOI - 10.1002/ajhb.10028
Subject(s) - locus (genetics) , allele , genetics , biology , population , evolutionary biology , demography , gene , sociology
The genetic analysis of a new trinucleotide repeat (D5S373) was carried out with a view to its application in both individual genetic profiling and human population genetics. In a screening analysis from seven world populations (n = 706) and after nucleotide sequence analysis, up to nine alleles were found corresponding to 8–13 repetitions of a TAA motif. This analysis shows He values ranging between 0.689–0.762. D5S373 reveals interpopulational variability which leads to specific frequency profiles in the major human groups, with alleles 8, 11, l2, and 13 being particularly informative, which suggests the that this marker may be of interest in the biological study of human populations. Am. J. Hum. Biol. 14:347–350, 2002. © 2002 Wiley‐Liss, Inc.