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Human immunodeficiency virus rather than hepatitis C virus infection is relevant to the development of an anti‐cardiolipin antibody
Author(s) -
Gotoh Moritaka,
Matsuda Juzo
Publication year - 1995
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830500312
Subject(s) - hepatitis c virus , virology , virus , antibody , medicine , human immunodeficiency virus (hiv) , immunology , cardiolipin , viral disease , biology , phospholipid , membrane , genetics
We have investigated whether or not a relationship exists between anti‐cardiolipin antibody (aCL) positivity and human immunodeficiency virus type 1 (HIV) and/or hepatitis C virus (HCV), and we have attempted to clarify which virus has close association with the development of aCL. We found that aCL positivity in HIV‐infected patients was significantly higher than in HCV‐infected patients. Furthermore, HIV/HCV dual‐infected patients exhibited a higher aCL positivity than patients infected by HCV alone. From these results, we conclude that HIV rather than HCV plays an important role in the development of aCL.