Premium
Promace day 1/MOPP day 8 chemotherapy for prolymphocytic leukemia: A case report of prolonged survival
Author(s) -
Yuen Benjamin H.,
Godwin John E.
Publication year - 1994
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830460313
Subject(s) - prolymphocytic leukemia , chemotherapy , medicine , regimen , leukemia , lymphoma , combination chemotherapy , gastroenterology , surgery , oncology , chronic lymphocytic leukemia
The treatment result of a case of de novo B‐cell prolymphocytic leukemia (B‐PLL) is described. The diagnosis was established with histologic, ultrastructural and immunologic studies. The patient was treated with chemotherapy using a total of seven cycles of ProMACE Day 1/MOPP Day 8 lymphoma regimen. Complete remission was achieved after 5 cycles of chemotherapy. The patient remains disease free after a 7‐year follow up. This is the first case of PLL being treated with such a regimen and the only case reported achieved such prolonged survival. Results of other treatment modalities are reviewed. © 1994 Wiley‐Liss, Inc.