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Hemolytic uremic syndrome developing during remission of acute myelomonocytic leukemia
Author(s) -
Okumura Hirokazu,
Nakamura Shinobu,
Ohtake Shigeki,
Yoshida Takashi,
Kobayashi Kazumi,
Okabe Yohko,
Matano Sadaya,
Kyohda Katsunori,
Matsuda Tamotsu
Publication year - 1993
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830440115
Subject(s) - medicine , acute myelomonocytic leukemia , chemotherapy , complication , complete remission , leukemia , induction chemotherapy , surgery
A 47‐year‐old woman was diagnosed with acute myelomonocytic leukemia (AMMoL) and was treated with combination chemotherapy. After one cycle of remission induction therapy, she entered into complete remission and then received three cycles of consolidation therapy. A month after the last consolidation therapy, she was diagnosed with having the complication of chemotherapy‐related HUS (C‐HUS). The C‐HUS improved after initiation of plasma exchange and antiplatelet therapy. In the present case, it seems that the antileukemic agents might play an important role in the development of C‐HUS. © 1993 Wiley‐Liss, Inc.