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Presence of serum antibodies to coagulation protein C in patients with systemic lupus erythematosus is not associated with antigenic or functional protein c deficiencies
Author(s) -
RuizArguelles Alejandro,
VazquezPrado Jose,
Deleze Margarita,
PerezRomano Beatriz,
Drenkard Cristina,
AlarconSegovia Donato,
RuizArguelles Guillermo J.
Publication year - 1993
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830440112
Subject(s) - medicine , antibody , immunology , antigen , coagulation , systemic lupus , lupus erythematosus , disease
Antibodies directed to immunopurified coagulation protein C (PC) were investigated in serum samples from 108 patients with systemic lupus erythematosus (SLE) and found in 12 of them. However, their presence was not associated with antigenic or functional deficiencies of PC, which were documented in 6 and 17 patients, respectively. © 1993 Wiley‐Liss, Inc.