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DNA diagnosis for the detection of sickle hemoglobinopathies
Author(s) -
Steinberg Martin H.
Publication year - 1993
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830430208
Subject(s) - prenatal diagnosis , confusion , medicine , pregnancy , disease , genotype , hemoglobinopathy , clinical phenotype , phenotype , genetics , biology , fetus , gene , psychology , psychoanalysis
At this time, the sole generally accepted use for DNA diagnosis in the hemoglobinopathies is for the prenatal detection of disease, which can be identified by these means early in the first trimester of pregnancy. By ascertaining genotype rather than phenotype, the confusion that results from diagnostic errors should be diminished. DNA diagnostics are the future of all genetic disease detection and this future will soon be upon us.