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Ultrastructure of plasma cells in a patient with J chain disease
Author(s) -
Sawamura Morio,
Kurabayashi Hitoshi,
Murakami Hirokazu,
Sakura Tohru,
Tamura Jun'Ichi,
Kubota Kazuo,
Naruse Takuji,
Tsuchiya Jun
Publication year - 1993
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830430116
Subject(s) - ultrastructure , protein filament , inclusion bodies , electron microscope , cytoplasm , pathology , multiple myeloma , disease , plasma cell , cytoplasmic inclusion , intermediate filament , inclusion (mineral) , chemistry , medicine , biology , microbiology and biotechnology , cell , cytoskeleton , physics , biochemistry , mineralogy , escherichia coli , optics , gene
Ultrastructural analysis of plasma cells was performed in a 74‐year‐old female patient with J chain disease. By electron microscopy, various characteristic findings were observed: lobulated nuclei, multinuclei, single sac loop‐like structures, flocculent filament‐like substances, nuclear inclusion bodies, cytoplasmic inclusion bodies, and multilamellar bodies. Our prior studies pointed out a poor prognosis in myeloma patients with these findings.
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