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Factor V inhibitor in thrombosis
Author(s) -
Kapur Ashok,
Kelsey Paul R.,
Isaacs Peter E. T.
Publication year - 1993
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830420410
Subject(s) - medicine , thrombosis , lupus anticoagulant , gangrene , amputation , anticoagulant , surgery , cardiology
A 68‐year‐old previously well woman developed sudden onset of limb gangrene in association with liver dysfunction. An immediately acting inhibitor to factor V with some of the features of lupus anticoagulant was demonstrated. The patient required limb amputation within 2 weeks and activity of the anticoagulant seemed to be on the decline 6 months later. © 1993 Wiley‐Liss, Inc.