Premium
Zinc abuse and sideroblastic anemia
Author(s) -
Ramadurai Jayanthi,
Shapiro Charles,
Kozloff Mark,
Telfer Margaret
Publication year - 1993
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830420217
Subject(s) - discontinuation , leukopenia , medicine , anemia , sideroblastic anemia , zinc , gastroenterology , bone marrow , chemotherapy , chemistry , organic chemistry
We report the case of a young woman who presented with anemia and leukopenia. A bone marrow aspirate, revealed a marked excess of ringed sideroblasts. A detailed dietary history disclosed excessive zinc intake. High serum zinc and low serum copper concentrations were confirmed. After discontinuation of the zinc supplements, she made a complete hematologic recovery. This report emphasises the importance of trace metals and their rote in the development of hematologic abnormalities. © 1993 Wiley‐Liss, Inc.