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Cobalamin absorption and hematologic status after two types of gastric surgery for obesity
Author(s) -
Yale Charles E.,
Gohdes Paul N.,
Schilling Robert F.
Publication year - 1993
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830420113
Subject(s) - microcytosis , medicine , anemia , cobalamin , gastric bypass surgery , gastroenterology , vitamin b12 , malabsorption , vitamin , stomach , surgery , obesity , gastric bypass , weight loss , iron deficiency
A series of morbidly obese patients was treated surgically with a gastric bypass, and a subsequent series received a vertical banded gastroplasty. To compare some of the nutritional effects of these two procedures we measured serum vitamin B 12 levels, absorption of food vitamin B 12 , frequency of microcytosis of erythrocytes, and frequency of anemia at one or more years after surgery. Patients with a gastric bypass showed greater weight loss, a greater frequency of microcytosis and anemia, more frequent subnormal serum levels of vitamin B 12 , and impressive failure to absorb food vitamin B 12 . Boiling the food containing vitamin B 12 led to increased absorption. © 1993 Wiley‐Liss, Inc.