Spontaneous remission of multilobated non‐Hodgkin lymphoma

A 67‐year‐old previously well man was admitted with hypercalcemia after a 7‐day history of fever, night sweats, and back pain. The blood showed 5% multilobated lymphoid cells. A multilobated non‐Hodgkin lymphoma associated with marked reticulin fibrosis was diagnosed on a bone marrow biopsy. During the next 7 days, in the absence of specific therapy, his symptoms disappeared. Three weeks after admission his biochemical abnormalities had resolved and after 9 weeks his bone marrow examination was normal. He remains in clinical and laboratory remission 16 months after presentation. © 1992 Wiley‐Liss, Inc.