Unexpectedly high toxicity of MACOP‐B in young patients with low grade lymphoma | Zendy

Arranz R. | Zendy; Peréz G. | Zendy; Steegmann J. L. | Zendy; Cámara R. | Zendy; Tomás J. F. | Zendy; Figuera A. | Zendy; Vazquez L. | Zendy; FernándezRañada J. M. | Zendy

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Unexpectedly high toxicity of MACOP‐B in young patients with low grade lymphoma

Author(s) -

Arranz R.,

Peréz G.,

Steegmann J. L.,

Cámara R.,

Tomás J. F.,

Figuera A.,

Vazquez L.,

FernándezRañada J. M.

Publication year - 1991

Publication title -

american journal of hematology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.456

H-Index - 105

eISSN - 1096-8652

pISSN - 0361-8609

DOI - 10.1002/ajh.2830380115

Subject(s) - medicine , neutropenia , lymphoma , complication , chemotherapy , toxicity , complete remission , surgery , gastroenterology

We report the results of treatment with MACOP‐B in 11 young patients with low grade lymphoma (LGL). Complete remission was obtained in 4 (57%) and partial remission in 3 (42.8%) of 7 evaluable patients. However, this aggressive chemotherapy has not offered any advantage because of an unacceptably high treatment‐related morbidity and mortality (17%). Serious infection during neutropenia was the most common complication.

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