Premium
Prompt engraftment using autologous peripheral blood stem cells for double autologous bone marrow rescue
Author(s) -
Hillyer Christopher D.,
Comenzo Raymond L.,
Miller Kenneth B.,
Schenkein David P.,
Tiegerman Karen O.,
Fogaren Terry A.,
Wazer David E.,
Parker Leroy,
Abrams Ross A.,
Desforges Jane F.,
Rudders Richard A.,
Berkman Eugene M.
Publication year - 1991
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830360217
Subject(s) - medicine , bone marrow , stem cell , chemotherapy , peripheral blood stem cells , peripheral blood , surgery , pathology , disease , immunology , hematopoietic stem cell transplantation , biology , genetics
A patient with Hodgkin's Disease, stage IIIA, was treated for recurrent disease with autologous peripheral blood stem cells after ablative chemotherapy. Bone marrow rescue occurred promptly and his disease was significantly reduced. Ablative chemotherapy was administered again and a second bone marrow rescue with peripheral blood stem cells was successful. Sequential peripheral blood stem cell bone marrow rescue, following high dose chemotherapy, may provide an alternative approach in selected patients.