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Effective therapy of human immunodeficiency virus‐associated anemia with recombinant human erythropoietin despite high endogenous erythropoietin
Author(s) -
Dacosta Noshir A.,
Hultin Mae B.
Publication year - 1991
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830360118
Subject(s) - erythropoietin , anemia , medicine , hemoglobin , recombinant dna , human immunodeficiency virus (hiv) , immunology , virology , biology , biochemistry , gene
A 32‐year‐old woman with human immunodeficiency virus (HIV) infection and progressive anemia presented to University Hospital with a hemoglobin of 3.4 g/dl. Because of her religious beliefs, she refused transfusion, and no iron or vitamin deficiency was found. She responded to recombinant human erythropoietin 150 U/kg intramuscularly thrice weekly with a rise in hemoglobin to 9.3 g/dl by 3 months of treatment. The serum erythropoietin level before treatment was markedly elevated at 1,340 mU/ml.