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Ph chromosome in a patient with non‐leukemic non‐hodgkin B‐cell lymphoma
Author(s) -
Fujii Hiroshi,
Yashige Hiromi,
Misawa Shinichi,
Tanaka Shinji,
Urata Yohji,
Matuyama Fumio
Publication year - 1990
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830350315
Subject(s) - lymphoma , medicine , chromosome , cancer research , oncology , hodgkin lymphoma , genetics , biology , gene
A standard Philadelphia translocation, t(9;22) (q34;q11), was found in lymph node cells from a patient with non‐leukemic non‐Hodgkin lymphoma at the time of diagnosis. The rearrangement of the breakpoint cluster region (bcr) was not detected with a bcr‐3′ probe. The neoplastic clone was of monoclonal B‐cell character with E‐, CD5‐, CD10‐, CD13‐, CD19+, CD20+, CD21+, CD25‐, HLA DR+, and positive surface lg(kappa). The patient showed no evidence of chronic myelogenous leukemia.