Structure of the granulocyte macrophage colony‐stimulating factor gene in patients with the myelodysplastic syndromes | Zendy

Boultwood Jacqueline | Zendy; Abrahamson Gail | Zendy; Buckle Veronica J. | Zendy; Rack Katrina | Zendy; Oscier David G. | Zendy; Wainscoat James S. | Zendy

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Structure of the granulocyte macrophage colony‐stimulating factor gene in patients with the myelodysplastic syndromes

Author(s) -

Boultwood Jacqueline,

Abrahamson Gail,

Buckle Veronica J.,

Rack Katrina,

Oscier David G.,

Wainscoat James S.

Publication year - 1990

Publication title -

american journal of hematology

Language(s) - English

Resource type - Journals

SCImago Journal Rank - 2.456

H-Index - 105

eISSN - 1096-8652

pISSN - 0361-8609

DOI - 10.1002/ajh.2830340215

Subject(s) - myelodysplastic syndromes , granulocyte macrophage colony stimulating factor , granulocyte , gene , chromosome , immunology , chromosome 7 (human) , cancer research , granulocyte colony stimulating factor , medicine , biology , genetics , cytokine , bone marrow , chemotherapy

DNA samples from 76 patients with the myelodysplastic syndromes, including 10 cases with a partial deletion of the long arm of chromosome 5 (5q‐), were examined for structural rearrangements of the granulocyte/macrophage colony‐stimulating factor (GM‐CSF) gene. No abnormalities were detected, indicating that structural aberrations of this gene are not a feature of the myelodysplastic syndromes.

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