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Transformation of refractory anemia with excess of blasts into acute myelogenous leukemia with Ph‐negative chronic myelogenous leukemia‐like characteristics
Author(s) -
Yamauchi Kunihiko,
Arimori Shigeru,
Nagao Tadami
Publication year - 1990
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830330114
Subject(s) - chronic myelogenous leukemia , medicine , leukemia , refractory (planetary science) , myeloid leukemia , anemia , refractory anemia , myeloid , immunology , gastroenterology , myelodysplastic syndromes , biology , bone marrow , astrobiology
We report a 56 year old patient with acute myelogenous leukemia (FAB classification: M2), in whom the number of mature myeloid cells similar to those seen in Ph‐negative chronic myelogenous leukemia increased markedly 2 months after the diagnosis of refractory anemia with excess of blasts (RAEB). This is a rare case of leukemic evolution as a terminal event of RAEB.