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Alveolar cell carcinoma complicating sickle cell anemia: A chance occurrence?
Author(s) -
Labi Marlon,
Haponik Edward F.,
Welsh Ronald A.,
Summer Warren R.
Publication year - 1989
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830320312
Subject(s) - medicine , malignancy , disease , pathology , sickle cell anemia , cell , carcinoma , differential diagnosis , lung , large cell , oncology , adenocarcinoma , cancer , biology , genetics
Alveolar cell carcinoma, a neoplasm associated with pre‐existing inflammatory lung disease, has not been reported previously in patients with sickle cell disease. We present such a patient and suggest that chronic pulmonary scarring in this setting predisposed to development of his malignancy. As survival increases in individuals with sickle cell disease, alveolar cell carcinoma must be considered in these differential diagnosis of otherwise unexplained chronic pulmonary infiltrates.