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Durable remission of pure red cell aplasia after treatment with high‐dose intravenous gammaglobulin and prednisone
Author(s) -
Needleman Samuel W.
Publication year - 1989
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830320216
Subject(s) - prednisone , pure red cell aplasia , aplasia , medicine , gamma globulin , toxicity , antibody , gastroenterology , immunology , anemia
Pure red cell aplasia (PRCA) is a rare disorder of erythrocyte production believed to have an autoimmune basis in most cases. Responses to a variety of immunosuppressive regimens are regularly observed, but toxicity is considerable. Brief responses to high‐dose intravenous immunoglobulin (IVIg) have been previously reported. This case demonstrates a durable clinical remission of PRCA treated with IVIg and glucocorticoids.