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Steroid‐responsive pure red cell aplasia associated with natural killer cell lymphocytosis
Author(s) -
Tefferi Ayalew,
Windebank Kevin P.,
Veeder Michael H.,
Kiely Joseph M.
Publication year - 1989
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830310313
Subject(s) - lymphocytosis , pure red cell aplasia , medicine , aplasia , immunology , bone marrow
A patient with pure red cell aplasia and expansion of the peripheral blood natural killer (NK) cell population is described. Despite normal absolute and differential leukocyte counts, NK cells were increased at diagnosis and at relapse. Furthermore, these cells were not morphologically recognizable on the peripheral blood smear examination. A favorable clinical response to glucocorticoid therapy was accompanied by a decrease in NK cells.