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Modified osmotic fragility test for the laboratory diagnosis of hereditary spherocytosis
Author(s) -
Judkiewicz Luba,
Bartosz Grzegorz,
Oplatowska Anna,
Szczepanek Andrzej
Publication year - 1989
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830310214
Subject(s) - hereditary spherocytosis , erythrocyte fragility , hemolysis , fragility , spherocytosis , tonicity , medicine , chemistry , splenectomy , spleen
A modified osmotic fragility test, based on measurement of hemolysis in four hypotonic NaCl solutions and logarithmic linearization of osmotic fragility curve is, like the “Pink test,” a specific and sensitive test for the laboratory diagnosis of hereditary spherocytosis.
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