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Pituitary abscess after autologous bone marrow transplantation
Author(s) -
Leff Richard S.,
Martino Roy L.,
Pollock W. James,
Knight William A.
Publication year - 1989
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830310113
Subject(s) - medicine , abscess , cyclophosphamide , bone marrow , surgery , lymphoma , transplantation , bone marrow transplantation , total body irradiation , autopsy , pathology , chemotherapy
The first case of pituitary abscess arising in a patient during recovery from autologous bone marrow transplantation is reported. A 31‐year‐old man with a 9 month history of T‐cell lymphoma died suddenly more than 60 days after successful treatment with high‐dose cyclophosphamide, total body irradiation, and autologous bone marrow infusion. Autopsy revealed a pituitary abscess associated with clinically silent sphenoid sinusitis. Unique aspects of this case are presented and clinical and pathologic features of pituitary abscess are reviewed. Although rare, pituitary abscess may complicate recovery from bone marrow transplantation.