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Apparent response of refractory post‐transfusion purpura to splenectomy
Author(s) -
Cunningham C. Casey,
Lind Stuart E.
Publication year - 1989
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830300211
Subject(s) - splenectomy , refractory (planetary science) , medicine , purpura (gastropod) , platelet , platelet transfusion , gamma globulin , surgery , spleen , immunology , antibody , ecology , physics , astrobiology , biology
Post transfusion purpura (PTP) is a rare disorder characterized by the abrupt onset of severe thrombocytopenia following transfusion. A patient with PTP and massive bleeding was refractory to corticosteroids, gamma globulin, and plasma exchange but developed an immediate and sustained rise in platelet count following splenectomy. Splenectomy may be a useful therapeutic modality in patients with refractory PTP.