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Diffuse panbronchiolitis as a pulmonary complication in patients with adult T‐cell leukemia
Author(s) -
Ono Kazutoshi,
Shimamoto Yoshinori,
Matsuzaki Miwako,
Sano Masayuki,
Yamaguchi Tsuneko,
Kato Osamu,
Yamada Hozumi,
Yamaguchi Masaya
Publication year - 1989
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830300207
Subject(s) - diffuse panbronchiolitis , complication , incidence (geometry) , medicine , t cell leukemia , leukemia , gastroenterology , immunology , biology , microbiology and biotechnology , antibiotics , physics , erythromycin , optics
Forty‐three cases of adult T‐cell leukemia (ATL) admitted to our hospital between 1982 and 1987 were studied. Three of those were found to be complicated with diffuse panbronchiolitis (DPB). The incidence of DPB is considered to be significantly higher in patients with ATL. The three DPB‐complicated cases composed one case each of the smoldering, chronic, and acute type of ATL. In each type, DPB preceded overt ATL and Candida afbicans was found in sputa following detection for bacteria. The DPB complication apparently worsened the prognosis of the ATL patients. We have discussed a possible relationship between ATL and DPB.