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T(8;21) With a phenotype of chronic myeloid leukemia
Author(s) -
Raskind Wendy H.,
Papayannopoulou Thalia,
Hammond William P.
Publication year - 1988
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830280410
Subject(s) - myeloid leukemia , phenotype , myeloproliferative disorders , myeloid , medicine , immunology , leukemia , cancer research , biology , genetics , gene
A myeloproliferative disorder having the phenotype of chronic myeloid leukemia (CML) with t(8;21) is reported. Neither t(9;22) nor a DNA rearrangement in the bcr region was detected. The presence of t(8;21), in contrast with previous experience, does not appear to prevent full maturation of the granulocytic series.