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Intrasplenic lymphoma resembling multiple hematomas in a hemophiliac
Author(s) -
Sweeney Joseph D.,
Hassett James M.
Publication year - 1988
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830280311
Subject(s) - medicine , splenectomy , lymphoma , surgery , hematoma , population , radiology , spleen , pathology , environmental health
A 42‐year‐old patient with hemophilia A developed acute left hypochondrial pain 8 days postnephrolithotomy. A colloidal scan indicated multiple hematomas, and conservative management was given. Postoperatively, recurrent discomfort necessitated splenectomy. Multiple space‐occupying lesions were found, and the histology was that of a large, noncleaved lymphoma. Contiguous spread outside of the capsule was evident, but abdominal nodes and liver appeared normal. Chemotherapy was administered, with evidence of tumor response, but refractoriness supervened, and the patient died 4 months after the diagnosis. Space‐occupying lesions in a hemophiliac are generally ascribed to hematomas. The exposure of this population to the human immunodeficiency virus (HIV) should raise the consideration of a non‐Hodgkin lymphoma in any situation where rapid clinical resolution of a hematoma is not occurring.