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Plasma cell leukemia with iga paraproteinemia and hyperviscosity
Author(s) -
Kosmo Michael A.,
Gale Robert Peter
Publication year - 1988
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830280210
Subject(s) - paraproteinemia , hyperviscosity syndrome , hyperviscosity , plasma cell leukemia , plasmapheresis , medicine , paraproteins , monoclonal gammopathy , plasma cell , paraproteinemias , leukemia , monoclonal gammopathy of undetermined significance , multiple myeloma , chronic lymphocytic leukemia , gammopathy , chemotherapy , monoclonal , pathology , immunology , antibody , monoclonal antibody , blood viscosity
Abstract Primary IgA plasma cell leukemia is a rare disorder in which hyperviscosity has not been reported. We studied a patient with plasma cell leukemia and IgA lambda monoclonal gammopathy with an elevated relative serum viscosity and congestive heart failure. Plasmapheresis and chemotherapy were successful in controlling symptoms. We discuss this unusual association and review the literature.