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Procainamide‐associated pancytopenia
Author(s) -
Shields Anthony F.,
Berenson Jeffrey A.
Publication year - 1988
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830270413
Subject(s) - pancytopenia , procainamide , medicine , bone marrow , anemia , hypoplasia , drug holiday , surgery , immunology , human immunodeficiency virus (hiv)
A 42‐year‐old male developed thrombocytopenia and anemia along with agranulocytosis during treatment with procainamide. Bone marrow hypoplasia was evident on biopsy, and the patient was without evidence of systemic lupus erythematosis. He had prompt marrow recovery on drug withdrawal. While procainamide‐induced agranulocytosis has been reported on a number of occasions, this is only the second case of pancytopenia.