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The first report of familial adult T‐cell leukemia lymphoma in the United States
Author(s) -
Denic Srdjan,
Abramson Jonathan,
Anandakrishnan Ravi,
Krishnamurthy Muthuswamy,
Dosik Harvey
Publication year - 1988
Publication title -
american journal of hematology
Language(s) - English
Resource type - Journals
SCImago Journal Rank - 2.456
H-Index - 105
eISSN - 1096-8652
pISSN - 0361-8609
DOI - 10.1002/ajh.2830270410
Subject(s) - medicine , lymphoma , leukemia , oncology , cancer research
Two patients, a daughter and her father, developed the acute type of adult T‐cell leukemia/lymphoma (ATLL) within a 3‐month period. Antibodies against HTLV‐I have been found in both wives of the father. The second wife acquired the infection from her husband within 3 years of marriage. The patients described represent the first cases of familial ATLL in the United States. ATLL continues to be frequently misdiagnosed in the United States. A positive family history consistent with this disease in a patient with a lymphoid malignancy may be a helpful clue for earlier diagnosis.